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BRAF A33T - Gene Variant Detail

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Gene BRAF
Variant A33T
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions BRAF A33T does not lie within any known functional domains of the Braf protein (UniProt.org). A33T results in Erk pathway activation similar to wild-type Braf in cultured cells (PMID: 31515458), and therefore, is predicted to have no effect on Braf protein function.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF A33T

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Transcript NM_004333.6
gDNA chr7:g.140924607C>T
cDNA c.97G>A
Protein p.A33T
Source Database RefSeq
Genome Build GRCh38/hg38

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