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Gene BRAF
Variant K601_W604del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions BRAF K601_W604del results in the deletion of four amino acids in the protein kinase domain of the Braf protein from amino acids 601 to 604 (UniProt.org). K601_W604del has been identified in the scientific literature (PMID: 35598548), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF K601_W604del

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Transcript NM_004333.6
gDNA chr7:g.140753324_140753335del12
cDNA c.1802_1813del12
Protein p.K601_W604del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354609.2 chr7:g.140753324_140753335del12 c.1802_1813del12 p.K601_W604del RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753324_140753335del12 c.1802_1813del12 p.K601_W604del RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753324_140753335del12 c.1802_1813del12 p.K601_W604del RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753324_140753335del12 c.1802_1813del12 p.K601_W604del RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References