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Gene BRAF
Variant N581H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF N581H lies within the protein kinase domain of the Braf protein (UniProt.org). N581H has not been identified in the scientific literature, and therefore, its effect on Braf protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF N581X BRAF N581H

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Transcript NM_004333.6
gDNA chr7:g.140754187T>G
cDNA c.1741A>C
Protein p.N581H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004333.5 chr7:g.140754187T>G c.1741A>C p.N581H RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140754187T>G c.1741A>C p.N581H RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140754187T>G c.1741A>C p.N581H RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140754187T>G c.1741A>C p.N581H RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140754187T>G c.1741A>C p.N581H RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140754187T>G c.1741A>C p.N581H RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References