Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene BRAF
Variant V600_K601delinsEN
Impact List indel
Protein Effect unknown
Gene Variant Descriptions BRAF V600_K601delinsEN results in deletion of a valine (V) and a lysine (L) in the protein kinase domain of the Braf protein from amino acids 600 to 601, combined with the insertion of a glutamic acid (E) and an asparagine (N) at the same site (UniProt.org). V600_K601delinsEN has not been characterized and therefore, its effect on Braf protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF V600_K601delinsEN

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_004333.6
gDNA chr7:g.140753332_140753337delinsGTTCTC
cDNA c.1798_1803delinsGAGAAC
Protein p.V600_K601delinsEN
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354609.2 chr7:g.140753332_140753337delinsGTTCTC c.1798_1803delinsGAGAAC p.V600_K601delinsEN RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753332_140753337delinsGTTCTC c.1798_1803delinsGAGAAC p.V600_K601delinsEN RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753332_140753337delinsGTTCTC c.1798_1803delinsGAGAAC p.V600_K601delinsEN RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753332_140753337delinsGTTCTC c.1798_1803delinsGAGAAC p.V600_K601delinsEN RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140753332_140753337delinsGTTCTC c.1798_1803delinsGAGAAC p.V600_K601delinsEN RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140753332_140753337delinsGTTCTC c.1798_1803delinsGAGAAC p.V600_K601delinsEN RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries