BRAF V600_R603del
Gene Variant Detail

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Gene BRAF
Variant V600_R603del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions BRAF V600_R603del results in the deletion of four amino acids of the Braf protein from amino acids 600 to 603 (UniProt.org). V600_R603del has been identified in sequencing studies (PMID: 35910024), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Mar 2026).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF V600_R603del

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Transcript NM_004333.6
gDNA chr7:g.140753327_140753338del12
cDNA c.1798_1809del12
Protein p.V600_R603del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001378468.1 chr7:g.140753327_140753338del12 c.1798_1809del12 p.V600_R603del RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753327_140753338del12 c.1798_1809del12 p.V600_R603del RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753327_140753338del12 c.1798_1809del12 p.V600_R603del RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753327_140753338del12 c.1798_1809del12 p.V600_R603del RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References