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Gene MAP2K1
Variant P124M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MAP2K1 P124M lies within the protein kinase domain of the Map2k1 protein (UniProt.org). P124M has not been characterized in the scientific literature and therefore, its effect on Map2k1 protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance
Category Variants Paths

MAP2K1 mutant MAP2K1 P124M

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Transcript NM_002755.4
gDNA chr15:g.66436824_66436825delCCinsAT
cDNA c.370_371delCCinsAT
Protein p.P124M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002755.3 chr15:g.66436824_66436825delCCinsAT c.370_371delCCinsAT p.P124M RefSeq GRCh38/hg38
XM_017022411.3 chr15:g.66436824_66436825delCCinsAT c.370_371delCCinsAT p.P124M RefSeq GRCh38/hg38
NM_002755.4 chr15:g.66436824_66436825delCCinsAT c.370_371delCCinsAT p.P124M RefSeq GRCh38/hg38
XM_017022411.2 chr15:g.66436824_66436825delCCinsAT c.370_371delCCinsAT p.P124M RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References