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Gene ARID1B
Variant Q127_Q131del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions ARID1B Q127_Q131del results in the deletion of five amino acids in the Arid1b protein from amino acids 127 to 131 (UniProt.org). Q127_Q131del has been identified in the scientific literature (PMID: 36374558), but has not been biochemically characterized and therefore, its effect on Arid1b protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

ARID1B mutant ARID1B Q127_Q131del

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Transcript NM_017519.2
gDNA chr6:g.156778310_156778324del15
cDNA c.381_395del15
Protein p.Q127_Q131del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001346813.1 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
NM_017519.2 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
NM_020732.3 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
XM_011535984.2 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
XM_017011106.2 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
XM_017011107.2 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
XM_017011103.2 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
XM_017011105.2 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38
XM_017011104.1 chr6:g.156778310_156778324del15 c.381_395del15 p.Q127_Q131del RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References