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Gene SMARCA4
Variant E821D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions SMARCA4 E821D lies within the ATP-binding helicase domain of the Smarca4 protein (UniProt.org). E821D has not been characterized in the scientific literature and therefore, its effect on Smarca4 protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

SMARCA4 mutant SMARCA4 E821D

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Transcript NM_003072.5
gDNA chr19:g.11018981G>C
cDNA c.2463G>C
Protein p.E821D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001128845.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128849.3 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451660.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451663.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128845.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128844.3 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128848.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128848.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439250.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001374457.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439243.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451662.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128846.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439247.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_003072.5 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001411150.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_006722845.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451661.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451667.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_003072.3 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001387283.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451658.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439244.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439249.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451667.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451664.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128847.4 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128849.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439246.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128847.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439251.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_006722846.3 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_011528198.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451661.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128844.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_011528198.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451665.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_006722846.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451663.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_047439248.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451659.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451666.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
NM_001128846.2 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38
XM_024451658.1 chr19:g.11018981G>C c.2463G>C p.E821D RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References