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Gene ALK
Variant A1015T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ALK A1015T lies within the EGF-like region of the Alk protein (UniProt.org). A1015T has been identified in the scientific literature (PMID: 37000961), but has not been biochemically characterized and therefore, its effect on Alk protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

ALK mutant ALK A1015T

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Transcript NM_004304.5
gDNA chr2:g.29226946C>T
cDNA c.3043G>A
Protein p.A1015T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004304.4 chr2:g.29226946C>T c.3043G>A p.A1015T RefSeq GRCh38/hg38
NM_004304.5 chr2:g.29226946C>T c.3043G>A p.A1015T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References