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| Gene | ALK |
| Variant | A528T |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | ALK A528T lies within MAM domain 2 of the Alk protein (UniProt.org). A528T has not been characterized in the scientific literature and therefore, its effect on Alk protein function is unknown (PubMed, May 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
ALK mutant ALK A528T |
| Transcript | NM_004304.5 |
| gDNA | chr2:g.29318369C>T |
| cDNA | c.1582G>A |
| Protein | p.A528T |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_004304.5 | chr2:g.29318369C>T | c.1582G>A | p.A528T | RefSeq | GRCh38/hg38 |
| NM_001353765.2 | chr2:g.29193301C>T | c.1582G>A | p.A528T | RefSeq | GRCh38/hg38 |
| NM_004304.4 | chr2:g.29318369C>T | c.1582G>A | p.A528T | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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