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Gene | RET |
Variant | L730R |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | RET L730R lies within the protein kinase domain of the Ret protein (UniProt.org). L730R has been identified in the scientific literature (PMID: 37743366), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Apr 2024). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET L730R |
Transcript | NM_020975.6 |
gDNA | chr10:g.43116636T>G |
cDNA | c.2189T>G |
Protein | p.L730R |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_020975.6 | chr10:g.43116636T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_001406743.1 | chr10:g.43116636T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_001406761.1 | chr10:g.43118406T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_001406759.1 | chr10:g.43116636T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_001406762.1 | chr10:g.43118406T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_020630.7 | chr10:g.43116636T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_001406744.1 | chr10:g.43116636T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_001406764.1 | chr10:g.43118406T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
NM_001406760.1 | chr10:g.43116636T>G | c.2189T>G | p.L730R | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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