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Gene | RET |
Variant | G736A |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | RET G736A lies within the protein kinase domain of the Ret protein (UniProt.org). G736A has been identified in the scientific literature (PMID: 37743366), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Apr 2024). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET G736A |
Transcript | NM_020975.6 |
gDNA | chr10:g.43116654G>C |
cDNA | c.2207G>C |
Protein | p.G736A |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001406759.1 | chr10:g.43116654G>C | c.2207G>C | p.G736A | RefSeq | GRCh38/hg38 |
NM_020975.6 | chr10:g.43116654G>C | c.2207G>C | p.G736A | RefSeq | GRCh38/hg38 |
NM_001406774.1 | chr10:g.43121947G>C | c.2207G>C | p.G736A | RefSeq | GRCh38/hg38 |
NM_001406744.1 | chr10:g.43116654G>C | c.2207G>C | p.G736A | RefSeq | GRCh38/hg38 |
NM_020630.7 | chr10:g.43116654G>C | c.2207G>C | p.G736A | RefSeq | GRCh38/hg38 |
NM_001406743.1 | chr10:g.43116654G>C | c.2207G>C | p.G736A | RefSeq | GRCh38/hg38 |
NM_001406760.1 | chr10:g.43116654G>C | c.2207G>C | p.G736A | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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