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Gene | FGFR2 |
Variant | R255W |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FGFR2 R255W lies within the extracellular domain of the Fgfr2 protein (UniProt.org). R255W has been identified in sequencing studies (PMID: 37964396, PMID: 37682528), but has not been biochemically characterized and therefore, its effect on Fgfr3 protein function is unknown (PubMed, May 2025). |
Associated Drug Resistance | |
Category Variants Paths |
FGFR2 mutant FGFR2 exon7 FGFR2 R255W |
Transcript | NM_000141.5 |
gDNA | chr10:g.121520155G>A |
cDNA | c.763C>T |
Protein | p.R255W |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |