Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene BRAF
Variant A366P
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF A366P does not lie within any known functional domains of the Braf protein (UniProt.org). A366P is associated with EGFR inhibitor resistance in the context of an EGFR exon 19 deletion (PMID: 38838224), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance Y
Category Variants Paths

BRAF mutant BRAF A366P

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_004333.6
gDNA chr7:g.140794352C>G
cDNA c.1096G>C
Protein p.A366P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001378471.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
XM_017012559.2 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
NM_001374244.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
XM_047420769.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
XM_047420768.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
NM_001378469.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
XM_047420767.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38
NM_001374258.1 chr7:g.140794352C>G c.1096G>C p.A366P RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries