BRAF G469L
Gene Variant Detail

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Gene BRAF
Variant G469L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF G469L lies within the protein kinase domain of the Braf protein (UniProt.org). G469L has been identified in the scientific literature (PMID: 24035431, PMID: 26301799, PMID: 26200454), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, May 2025).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF G469X BRAF G469L

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Transcript NM_004333.6
gDNA chr7:g.140781602_140781603delGGinsCT
cDNA c.1405_1406delGGinsCT
Protein p.G469L
Source Database RefSeq
Genome Build GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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