Gene Variant Detail

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Gene BRAF
Variant G606V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRAF G606V lies within the protein kinase domain of the Braf protein (UniProt.org). G606V has been identified in sequencing studies (PMID: 21825258), but has not been biochemically characterized and therefore, its effect on Braf protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF G606V

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Transcript NM_004333.6
gDNA chr7:g.140753318C>A
cDNA c.1817G>T
Protein p.G606V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354609.1 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
XM_005250045 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
NM_004333 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753318C>A c.1817G>T p.G606V RefSeq GRCh38/hg38
NM_001378471.1 chr7:g.140749351C>A c.1817G>T p.G606V RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries