BRAF N581T
Gene Variant Detail

Request Content

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene BRAF
Variant N581T
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions BRAF N581T lies within the protein kinase domain of the Braf protein (UniProt.org). N581T has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Braf in culture (PMID: 29533785), and therefore, is predicted to have no effect on Braf protein function.
Associated Drug Resistance
Category Variants Paths

BRAF mutant BRAF N581X BRAF N581T

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_004333.6
gDNA chr7:g.140753393T>G
cDNA c.1742A>C
Protein p.N581T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004333 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38
NM_004333.6 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38
NM_001354609.1 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38
XM_005250045 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38
NM_004333.5 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38
NM_001378474.1 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38
NM_001354609.2 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38
NM_001378468.1 chr7:g.140753393T>G c.1742A>C p.N581T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries