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Gene | IDH2 |
Variant | wild-type |
Impact List | none |
Protein Effect | no effect |
Gene Variant Descriptions | Wild-type IDH2 indicates that no mutation has been detected within the IDH2 gene. |
Associated Drug Resistance | |
Category Variants Paths |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
IDH2 wild-type | high grade glioma | not applicable | N/A | Guideline | Risk Factor | IDH2 wild-type is associated with increased risk of aggressive disease in patients with grade II or III infiltrative gliomas (NCCN.org). | detail... |
IDH2 wild-type | IDH-wildtype glioblastoma | not applicable | N/A | Guideline | Diagnostic | Wild-type IDH2 aids in the diagnosis of glioblastoma (NCCN.org). | detail... |