NTRK2 S257F
Gene Variant Detail

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Gene NTRK2
Variant S257F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions NTRK2 S257F lies within Ig-like C2-type domain 1 of the Ntrk2 protein (UniProt.org). S257F has been identified in sequencing studies (PMID: 22810696, PMID: 39453824), but has not been biochemically characterized and therefore, its effect on Ntrk2 protein function is unknown (PubMed, Jul 2026).
Associated Drug Resistance
Category Variants Paths

NTRK2 mutant NTRK2 S257F

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Transcript NM_001018064.3
gDNA chr9:g.84724273C>T
cDNA c.770C>T
Protein p.S257F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017014751.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369538.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018065.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018066.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014752 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018066.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018064.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014759 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369533.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014761 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252001.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_006180.6 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252004.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014753 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_047423433.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252004.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014758.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014757.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014759.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018064.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014760 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252003.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001291937 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014752.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_011518720.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369544.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014761.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369540.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369534.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_006180.4 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014755.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014753.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001007097.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252001.4 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369539.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369543.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369545.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252007 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252003.4 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252001 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014754.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252007.4 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018065 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014751.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014756.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252006.4 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_047423432.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369532.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001007097 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014755.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014751 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252006 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_006180 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369537.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018066 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001291937.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001007097.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014760.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001291937.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369547.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014755 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369549.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252003 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_011518718.4 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014753.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369541.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014758 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018064 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369542.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014760.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014752.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369548.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014757 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001018065.2 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_011518718 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_011518720 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014756 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_005252004 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
NM_001369546.1 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_017014754 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38
XM_011518718.3 chr9:g.84724273C>T c.770C>T p.S257F RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References