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Gene RAD51D
Variant A152D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RAD51D A152D does not lie within any known functional domains of the Rad51d protein (UniProt.org). A152D has not been characterized in the scientific literature and therefore, its effect on Rad51d protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

RAD51D mutant RAD51D A152D

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Transcript NM_002878.4
gDNA chr17:g.35107013G>T
cDNA c.455C>A
Protein p.A152D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002878 chr17:g.35107013G>T c.455C>A p.A152D RefSeq GRCh38/hg38
NM_002878.3 chr17:g.35107013G>T c.455C>A p.A152D RefSeq GRCh38/hg38
NM_002878.4 chr17:g.35107013G>T c.455C>A p.A152D RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
RAD51D mutant breast cancer not applicable N/A Guideline Risk Factor Germline RAD51D mutations are associated with increased risk of developing breast cancer (NCCN.org). detail...
RAD51D mutant ovarian cancer not applicable N/A Guideline Risk Factor Germline RAD51D mutations are associated with increased risk of developing ovarian cancer (NCCN.org). detail...