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| Profile Name | ABL1 G250R ABL1 G251D |
| Gene Variant Detail | |
| Relevant Treatment Approaches |
| Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|---|
| ABL1 G250R ABL1 G251D | oral cavity cancer | no benefit | Nilotinib | Case Reports/Case Series | Actionable | In a clinical case study, Tasigna (nilotinib) treatment resulted in no benefit in a patient with oral cavity cancer harboring ABL1 G250R and G251D (PMID: 28514312). | 28514312 |