Molecular Profile Detail

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Profile Name CD274 pos STK11 mut
Gene Variant Detail

CD274 positive (unknown)

STK11 mutant (unknown)

Relevant Treatment Approaches

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05445843 Phase II JDQ443 Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression >= 1% and an STK11 Co-mutation. Active, not recruiting USA | TUR | NLD | ITA | HUN | GRC | GBR | FRA | ESP | DEU | BRA | BEL | AUT | ARG 5