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| Profile Name | PDGFRB W566R |
| Gene Variant Detail | |
| Relevant Treatment Approaches |
| Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|---|
| PDGFRB W566R | Advanced Solid Tumor | predicted - sensitive | Imatinib | Preclinical - Biochemical | Actionable | In a preclinical study, Gleevec (imatinib) treatment inhibited Pdgfrb activity in a reporter assay in a cell line expressing PDGFRB W566R (PMID: 39580648). | 39580648 |