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| Profile Name | ARID1A P549fs ARID1A N756fs |
| Gene Variant Detail | |
| Relevant Treatment Approaches |
| Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|---|
| ARID1A P549fs ARID1A N756fs | ovarian clear cell carcinoma | sensitive | Tulmimetostat | Preclinical - Cell line xenograft | Actionable | In a preclinical study, Tulmimetostat inhibited viability of an ovarian clear cell carcinoma cell line harboring ARID1A N756fs and P549fs in culture and inhibited tumor growth in a cell line xenograft model (PMID: 38833522). | 38833522 |