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| Molecular Profile | FGFR3 R248C |
| Therapy | Infigratinib |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR3 R248C | Advanced Solid Tumor | sensitive | Infigratinib | Preclinical - Cell culture | Actionable | In a preclinical study, Truseltiq (infigratinib) inhibited growth of transformed cells expressing FGFR3 R248C in culture (PMID: 23786770). | 23786770 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23786770) | Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. | Full reference... |