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| Molecular Profile | FGFR2 P253R |
| Therapy | Pazopanib |
| Indication/Tumor Type | head and neck squamous cell carcinoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 P253R | head and neck squamous cell carcinoma | predicted - sensitive | Pazopanib | Case Reports/Case Series | Actionable | In a clinical case study, treatment with Votrient (pazopanib) resulted in reduced tumor size in a patient with head and neck squamous cell carcinoma harboring FGFR2 P253R (PMID: 23786770). | 23786770 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23786770) | Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. | Full reference... |