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Molecular Profile | FGFR2 N549K |
Therapy | Derazantinib |
Indication/Tumor Type | endometrial cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR2 N549K | endometrial cancer | sensitive | Derazantinib | Preclinical - Cell culture | Actionable | In a preclinical study, Derazantinib (ARQ 087) inhibited growth of endometrial cancer cell lines harboring FGFR2 N549K in culture (PMID: 27627808). | 27627808 |
PubMed Id | Reference Title | Details |
---|---|---|
(27627808) | Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation. | Full reference... |