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| Molecular Profile | MERTK over exp |
| Therapy | RXDX-106 |
| Indication/Tumor Type | gastric adenocarcinoma |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| MERTK over exp | gastric adenocarcinoma | sensitive | RXDX-106 | Preclinical - Patient cell culture | Actionable | In a preclinical study, RXDX-106 inhibited proliferation of patient derived gastric cancer cells overexpressing Mertk (PMID: 29285287). | 29285287 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (29285287) | MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines. | Full reference... |