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Molecular Profile | TSC1 R98* |
Therapy | Everolimus |
Indication/Tumor Type | hepatocellular carcinoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
TSC1 R98* | hepatocellular carcinoma | predicted - sensitive | Everolimus | Case Reports/Case Series | Actionable | In a clinical study, a hepatocellular carcinoma patient harboring TSC1 R98* achieved stable disease following treatment with Afinitor (everolimus) (PMID: 30373752). | 30373752 |
PubMed Id | Reference Title | Details |
---|---|---|
(30373752) | Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies. | Full reference... |