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Molecular Profile BRAF K601E
Therapy U0126
Indication/Tumor Type melanoma
Response Type predicted - sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF K601E melanoma predicted - sensitive U0126 Preclinical - Cell culture Actionable In a preclinical study, U0126 treatment inhibited growth of melanoma cells harboring BRAF K601E in culture (PMID: 18794803). 18794803
PubMed Id Reference Title Details
(18794803) CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations. Full reference...