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Molecular Profile | BRAF amp |
Therapy | unspecified immune checkpoint inhibitor |
Indication/Tumor Type | lung non-small cell carcinoma |
Response Type | not predictive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF amp | lung non-small cell carcinoma | not predictive | unspecified immune checkpoint inhibitor | Clinical Study | Actionable | In a retrospective clinical study, no significant difference in overall survival (19.0 vs 18.4 months) was found in patients with non-small cell lung cancer harboring BRAF V600E (n=14), amplification (n=5), or non-V600E mutations (n=12) who received immunotherapy compared to those who never received immunotherapy (PMID: 31367539). | 31367539 |
PubMed Id | Reference Title | Details |
---|---|---|
(31367539) | Therapeutic outcomes in non-small cell lung cancer with BRAF mutations: a single institution, retrospective cohort study. | Full reference... |