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| Molecular Profile | TSC2 Q1178* |
| Therapy | Everolimus |
| Indication/Tumor Type | thyroid cancer |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| TSC2 Q1178* | thyroid cancer | predicted - sensitive | Everolimus | Case Reports/Case Series | Actionable | In a clinical case study, a thyroid cancer patient harboring TSC2 Q1178* demonstrated an 18-month response to Afinitor (everolimus) (PMID: 25295501; NCT00936858). | 25295501 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (25295501) | Response and acquired resistance to everolimus in anaplastic thyroid cancer. | Full reference... |