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Molecular Profile | CDKN2A del |
Therapy | unspecified immune checkpoint inhibitor |
Indication/Tumor Type | lung non-small cell carcinoma |
Response Type | not predictive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
CDKN2A del | lung non-small cell carcinoma | not predictive | unspecified immune checkpoint inhibitor | Clinical Study - Cohort | Actionable | In a retrospective analysis, homozygous deletion of CDKN2A or loss of function CDKN2A mutations in two cohorts of non-small cell lung cancer patients were not predictive of overall survival or time to treatment failure when treated with immune checkpoint inhibitors (PMID: 34074656). | 34074656 |
PubMed Id | Reference Title | Details |
---|---|---|
(34074656) | CDKN2A Alterations and Response to Immunotherapy in Solid Tumors. | Full reference... |