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Molecular Profile | CDKN2A del |
Therapy | unspecified immune checkpoint inhibitor |
Indication/Tumor Type | head and neck squamous cell carcinoma |
Response Type | not predictive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
CDKN2A del | head and neck squamous cell carcinoma | not predictive | unspecified immune checkpoint inhibitor | Clinical Study - Cohort | Actionable | In a retrospective analysis, homozygous deletion of CDKN2A or loss of function CDKN2A mutations in two cohorts of head and neck squamous cell carcinoma patients were not predictive of overall survival or time to treatment failure when treated with immune checkpoint inhibitors (PMID: 34074656). | 34074656 |
PubMed Id | Reference Title | Details |
---|---|---|
(34074656) | CDKN2A Alterations and Response to Immunotherapy in Solid Tumors. | Full reference... |