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Molecular Profile | RB1 inact mut |
Therapy | BAY 61-3606 |
Indication/Tumor Type | retinoblastoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
RB1 inact mut | retinoblastoma | sensitive | BAY 61-3606 | Preclinical | Actionable | In a preclinical study, a retinoblastoma cell line was sensitive to BAY 61-3606 in cell culture and in xenograft models, demonstrating increased apoptosis (PMID: 22237022). | 22237022 |
PubMed Id | Reference Title | Details |
---|---|---|
(22237022) | A novel retinoblastoma therapy from genomic and epigenetic analyses. | Full reference... |