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Molecular Profile | FBXW7 R465H |
Therapy | Temsirolimus |
Indication/Tumor Type | lung adenocarcinoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FBXW7 R465H | lung adenocarcinoma | sensitive | Temsirolimus | Case Reports/Case Series | Actionable | In a clinical case study, a patient with lung adenocarcinoma harboring FBXW7 R465H demonstrated tumor shrinkage when treated with Torisel (temsirolimus) (PMID: 24360397). | 24360397 |
PubMed Id | Reference Title | Details |
---|---|---|
(24360397) | Temsirolimus therapy in a patient with lung adenocarcinoma harboring an FBXW7 mutation. | Full reference... |