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Ref Type Journal Article
PMID (24360397)
Authors Villaruz LC, Socinski MA
Title Temsirolimus therapy in a patient with lung adenocarcinoma harboring an FBXW7 mutation.
Journal Vol Issue Date Pages Journal Short Title
Lung cancer (Amsterdam, Netherlands) 83 2 2014 Feb 300-1 Lung Cancer
URL
Abstract Text We report the identification of an FBXW7 mutation in a patient with adenocarcinoma of the lung, whose tumor had previously been shown to be EGFR and ALK wild type and who had previously progressed on multiple lines of systemic therapy. She experienced both clinical and radiographic benefit from treatment with the mTOR inhibitor temsirolimus.

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