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| Molecular Profile | FGFR2 S252W |
| Therapy | Pazopanib |
| Indication/Tumor Type | gallbladder adenocarcinoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 S252W | gallbladder adenocarcinoma | predicted - sensitive | Pazopanib | Case Reports/Case Series | Actionable | In a clinical case study, Votrient (pazopanib) treatment resulted in stable disease lasting over 2 years in a patient with metastatic gallbladder adenocarcinoma harboring FGFR2 S252W (PMID: 36307559). | 36307559 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (36307559) | Sustained response on sequential anti-FGFR therapy in metastatic gall bladder cancer: a case report and literature review. | Full reference... |