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Molecular Profile PIK3CA mutant
Therapy AZD8835
Indication/Tumor Type breast cancer
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
PIK3CA mutant breast cancer sensitive AZD8835 Preclinical Actionable In a preclinical study, AZD8835 inhibited tumor growth in breast cancer xenograft models harboring PIK3CA mutations (AACR; 2015. Abstract nr 2665). detail...
PubMed Id Reference Title Details
High dose intermittent scheduling of AZD8835, a novel potent and selective inhibitor of PI3K-alpha and PI3K-delta, identifies potential treatment strategies for PIK3CA-dependent cancers Full reference...