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| Molecular Profile | AXL positive |
| Therapy | ER-851 |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| AXL positive | Advanced Solid Tumor | sensitive | ER-851 | Preclinical - Cell culture | Actionable | In a preclinical study, ER-851 decreased viability of transformed cells expressing AXL in culture, and inhibited tumor growth in a cell line xenograft model (PMID: 36279567). | 36279567 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (36279567) | ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs. | Full reference... |