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Molecular Profile | CD274 positive |
Therapy | Ipilimumab + Nivolumab |
Indication/Tumor Type | lung squamous cell carcinoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
CD274 positive | lung squamous cell carcinoma | sensitive | Ipilimumab + Nivolumab | Guideline | Actionable | Combination Opdivo (nivolumab) plus Yervoy (ipilimumab) is in guidelines as first-line or continuation maintenance therapy for advanced or metastatic lung squamous cell carcinoma patients with CD274 (PD-L1) expression >1% and negative for actionable molecular biomarkers (NCCN.org). | detail... |
PubMed Id | Reference Title | Details |
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NCCN.org | Full reference... |