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Molecular Profile | CBL mutant |
Therapy | N/A |
Indication/Tumor Type | myelodysplastic/myeloproliferative neoplasm |
Response Type | not applicable |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
CBL mutant | myelodysplastic/myeloproliferative neoplasm | not applicable | N/A | Clinical Study | Prognostic | In clinical analyses, mutations in CBL were associated with adverse prognosis in patients with chronic myelomonocytic leukemia (PMID: 26230957, PMID: 23690417, PMID: 19901108). | 26230957 19901108 23690417 |
PubMed Id | Reference Title | Details |
---|---|---|
(26230957) | An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies. | Full reference... |
(23690417) | Prognostic score including gene mutations in chronic myelomonocytic leukemia. | Full reference... |
(19901108) | Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies. | Full reference... |