Profile Response Detail

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Molecular Profile BRAF D594G
Therapy Belvarafenib
Indication/Tumor Type mucosal melanoma
Response Type predicted - sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF D594G mucosal melanoma predicted - sensitive Belvarafenib Case Reports/Case Series Actionable In a clinical case study, Belvarafenib (HM95573) treatment resulted in a partial response ongoing at 8.5 months in a mucosal melanoma patient harboring BRAF D594G (PMID: 38470950). 38470950
PubMed Id Reference Title Details
(38470950) Exploring Molecular Genetic Alterations and RAF Fusions in Melanoma: A Belvarafenib Expanded Access Program in Patients with RAS/RAF-Mutant Melanoma. Full reference...