Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Molecular Profile | RAD51D K91Ifs*13 |
Therapy | Olaparib |
Indication/Tumor Type | ovarian cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
RAD51D K91Ifs*13 | ovarian cancer | sensitive | Olaparib | Preclinical - Cell culture | Actionable | In a preclinical study, Lynparza (olaparib) inhibited viability of ovarian cancer cell lines expressing RAD51D K91Ifs*13 in culture (PMID: 38905575). | 38905575 |
PubMed Id | Reference Title | Details |
---|---|---|
(38905575) | Germline Mutational Landscape and Novel Targetable RAD51D Variant in Chinese Patients With Ovarian Cancer. | Full reference... |