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Molecular Profile | EML4 - ALK |
Therapy | Crizotinib |
Indication/Tumor Type | malignant pleural mesothelioma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
EML4 - ALK | malignant pleural mesothelioma | predicted - sensitive | Crizotinib | Case Reports/Case Series | Actionable | In a clinical case study, Xalkori (crizotinib) treatment resulted in a partial response in a patient with malignant pleural mesothelioma harboring EML4-ALK (e6:e20) (PMID: 39534944). | 39534944 |
PubMed Id | Reference Title | Details |
---|---|---|
(39534944) | Case report: targeted therapy of malignant pleural mesothelioma with anaplastic lymphoma kinase receptor tyrosine kinase gene fusion mutation by crizotinib. | Full reference... |