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Molecular Profile | FGFR2 N549K |
Therapy | FIIN-1 |
Indication/Tumor Type | endometrial carcinoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR2 N549K | endometrial carcinoma | sensitive | FIIN-1 | Preclinical | Actionable | In a preclinical study, FIIN-1 inhibited proliferation of endometrial carcinoma cell lines harboring FGFR2 N549K mutation in culture (PMID: 20338520). | 20338520 |
PubMed Id | Reference Title | Details |
---|---|---|
(20338520) | A structure-guided approach to creating covalent FGFR inhibitors. | Full reference... |