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| Molecular Profile | CD274 over exp |
| Therapy | Pembrolizumab |
| Indication/Tumor Type | lung adenocarcinoma |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| CD274 over exp | lung adenocarcinoma | sensitive | Pembrolizumab | Guideline | Actionable | Keytruda (pembrolizumab) is included in guidelines as preferred first-line and as continued maintenance therapy for patients with advanced or metastatic lung adenocarcinoma, with CD274 (PD-L1) expression of 50% or more, and negative for actionable molecular biomarkers (category 1) (NCCN.org). | detail... |
| PubMed Id | Reference Title | Details |
|---|---|---|
| NCCN.org | Full reference... |