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| Molecular Profile | AXL over exp |
| Therapy | Bemcentinib |
| Indication/Tumor Type | prostate cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| AXL over exp | prostate cancer | sensitive | Bemcentinib | Preclinical | Actionable | In a preclinical study, Bemcentinib (BGB-324) inhibited growth of prostate cancer cell lines harboring elevated Axl protein level in culture (PMID: 26036314). | 26036314 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (26036314) | Axl receptor tyrosine kinase is up-regulated in metformin resistant prostate cancer cells. | Full reference... |