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| Molecular Profile | IDH1 mutant |
| Therapy | N/A |
| Indication/Tumor Type | glioblastoma |
| Response Type | not applicable |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| IDH1 mutant | glioblastoma | not applicable | N/A | Clinical Study | Prognostic | In multiple clinical studies, including two meta-analyses, IDH1 mutations were associated with a greater overall survival and progression-free survival in patients with glioblastoma (PMID: 23904262, PMID: 26945349, PMID: 20560678). | 20560678 23904262 26945349 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23904262) | IDH1 mutation is associated with improved overall survival in patients with glioblastoma: a meta-analysis. | Full reference... |
| (26945349) | Isocitrate Dehydrogenase (IDH)1/2 Mutations as Prognostic Markers in Patients With Glioblastomas. | Full reference... |
| (20560678) | Prognostic value of IDH1 mutations identified with PCR-RFLP assay in glioblastoma patients. | Full reference... |