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| Molecular Profile | MSH2 inact mut |
| Therapy | Baicalein |
| Indication/Tumor Type | colon cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| MSH2 inact mut | colon cancer | sensitive | Baicalein | Preclinical | Actionable | In a preclinical study, treatment with Baicalein resulted in decreased growth of azoxymethane/dextran sodium sulfate-induced colon tumors in a MSH2-deficient mouse model (PMID: 27262172). | 27262172 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (27262172) | A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies. | Full reference... |